Most important, they can't read the 3 billion letters--A, C, T and G, for the nucleotides adenine, cytosine, thymine and guanine--in the human genome from beginning to end, the way one reads a book.
The terms sense and antisense were coined by Paul Zamecnik to show the complementary, double-strand nature of DNA. One strand consisted of alternating patterns of the four nucleotides that make up DNA adenine, cytosine, guanine and thymine and it could be read in order.
The terms sense and antisense were coined by Paul Zamecnik to show the complementary, double-strand nature of DNA. One strand consisted of alternating patterns of the four nucleotides that make up DNA adenine, cytosine, guanine and thymine and it could be read in order.